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Biomedicine and Life Sciences
Biomedicine and Life Sciences

Science Advances

  • Volume 8
  • Issue 48
  • 02 Dec 2022
Go to Science Advances
Go to Science Advances

ONLINE COVER A smart dual hormone microneedle patch for blood glucose control. Insulin and glucagon secreted from the pancreas are essential for regulating blood glucose levels. Inspired by the dual-responsive mechanism, Yang et al. developed a glucose-responsive microneedle patch that enables closed-loop delivery of both insulin and glucagon for diabetes treatment. In a Type 1 diabetic pig model, the patch kept blood glucose levels within normal range and minimized the risk of hypoglycemia.

Credit: Yang et al./Science Advances

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Science Advances is the American Association for the Advancement of Science’s (AAAS) open access multidisciplinary journal, publishing impactful research papers and reviews in any area of science, in both disciplinary-specific and broad, interdisciplinary areas.

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